Crowley’s An Introduction to Human Disease (10th Edition)

$19.99

Download Crowley’s An Introduction to Human Disease (10th Edition) written by Emily Reisner, Howard Reisner in PDF format. This book is under the category Anatomy and bearing the isbn/isbn13 number 1284050238/9781284050233. You may reffer the table below for additional details of the book.

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Description

Reorganized and updated to provide a more accessible; student-friendly experience; Crowley’s An Introduction to Human Disease; 10th Edition (PDF) provides students with a clear; well-illustrated explanation of the structural and functional changes associated with a disease; the clinical manifestations of the disease; and how to determine treatment. The first chapters of the textbook discuss general concepts and diseases affecting the body as a whole. Later chapters consider the various organ systems and their diseases. The 10th Edition boasts a wealth of new disease photos; expanded and new case studies; and a robust student and instructor ancillary package.

NOTE: This sale only includes Crowley’s An Introduction to Human Disease 10e PDF. No online codes or other resources come with it.

Additional information

book-author

Emily Reisner, Howard Reisner

publisher

Jones – Bartlett Learning; 10th edition

file-type

PDF

pages

848 pages

language

English

asin

B01I5F56UA

isbn10

1284050238

isbn13

9781284050233

Table of contents


Table of contents :
Cover……Page 1
Title……Page 2
Copyright……Page 3
Contents
……Page 8
PREFACE……Page 24
ABOUT THE AUTHORS……Page 28
ACKNOWLEDGMENTS……Page 30
REVIEWERS……Page 32
A VISUAL WALKTHROUGH……Page 34
CASE STUDIES……Page 38
TEACHING AND LEARNING AIDS……Page 40
How Do We Know We Are Sick?……Page 42
Principles of Diagnosis……Page 43
The History……Page 44
The Physical Examination……Page 45
Choosing a Diagnostic Test……Page 46
Clinical Laboratory Tests……Page 47
Imaging Techniques……Page 49
Imaging Technology to Detect Specific Molecules and Processes……Page 55
Ultrasound……Page 58
Cytologic and Histologic Examinations……Page 59
Tests of Electrical Activity……Page 60
Treatment……Page 61
The Cell……Page 66
The Nucleus……Page 67
Major Cell Organelles and Their Functions……Page 69
Epithelium……Page 71
Muscle Tissue……Page 74
The Germ Layers and Their Derivatives……Page 75
Diffusion and Osmosis……Page 76
Active Transport……Page 78
Hypertrophy and Hyperplasia……Page 79
Metaplasia……Page 80
Cell Injury……Page 81
Cell Death and Cell Necrosis……Page 82
Programmed Cell Death: Apoptosis……Page 83
Aging and the Cell……Page 84
Introduction……Page 88
Genes and Inheritance Patterns……Page 89
X Chromosome Inactivation: The Lyon Hypothesis……Page 91
Chromosome Analysis……Page 92
The Structure of DNA in the Chromosomes……Page 93
Translation of DNA into Proteins……Page 95
Mitochondrial Genes and Inheritance……Page 96
Mitosis……Page 97
Meiosis……Page 99
Gametogenesis……Page 100
Comparison of Spermatogenesis and Oogenesis……Page 101
Single Nucleotide Polymorphisms……Page 102
Genes and Recombinant DNA Technology (Genetic Engineering)……Page 103
Introduction……Page 108
Harmful Drugs and Chemicals……Page 109
Maternal Infections……Page 111
Chromosomal Abnormalities……Page 114
Chromosome Deletions and Translocations During Gametogenesis……Page 115
Sex Chromosome Abnormalities……Page 117
Autosomal Abnormalities……Page 120
Genetically Transmitted Diseases……Page 122
Autosomal Dominant Inheritance……Page 124
Autosomal Recessive Inheritance……Page 125
Prenatal Diagnosis of Congenital Abnormalities……Page 127
Introduction: Host Defense……Page 134
The Inflammatory Reaction……Page 135
Local and Systemic Effects……Page 137
Chemical Mediators of Inflammation……Page 139
The Role of Lysosomal Enzymes in The Inflammatory Process……Page 141
Role of Inflammatory Cells in Antimicrobial Defense……Page 142
Terminology of Infection……Page 143
Introduction: The Body’s Defense Mechanisms……Page 148
Adaptive Immunity……Page 149
The Role of Lymphocytes in Adaptive Immunity……Page 150
Formation of Antigen Binding Regions in T and B Cells……Page 151
Selection of Antigen Receptors……Page 153
T Cell Types……Page 154
Antigen Dependent Lympocyte Maturation……Page 155
T Cell Independent and Dependent Humoral Responses……Page 159
Antigen Dependent Lymphocyte Proliferation: B Cells……Page 160
B Cell Class Switching, Affinity Maturation, and Plasma Cell Production……Page 161
Effector Molecules of Humoral Immunity: Immunoglobulins……Page 163
Immunoglobulin Effector Functions……Page 164
The Role of Complement in Immune Responses……Page 165
HLA Types and Susceptibility to Disease……Page 167
Hypersensitivity Reactions: Immune System—Related Tissue Injury……Page 168
Type I. Immediate Hypersensitivity Reactions: Allergy and Anaphylaxis……Page 169
Type II. Hypersensitivity Reactions……Page 171
Type III. Tissue Injury Caused by Immune Complexes (“Immune Complex Disease”)……Page 172
Chemical Agents (Drugs)……Page 173
Immunodeficiency Disease……Page 174
Mechanisms of Tolerance Generation……Page 175
Lupus Erythematosus……Page 176
Introduction……Page 186
Comparison of Benign and Malignant Tumors……Page 187
Development of Malignant Neoplasms……Page 192
Necrosis in Tumors……Page 195
Proto-Oncogenes……Page 197
Tumor Suppressor Genes……Page 198
Genes Regulating Apoptosis……Page 201
Multistep Progression of Genetic Changes Leading to Cancer……Page 202
Chemical Carcinogens……Page 203
Heredity and Tumors……Page 204
Early Recognition of Neoplasms……Page 205
Fine Needle Aspiation……Page 206
Tumor-Associated Antigen Tests……Page 207
Grading and Staging Malignant Tumors……Page 208
Anticancer Drugs……Page 209
Immunotherapy……Page 211
Survival Rates in Neoplastic Disease……Page 213
Classification of Bacteria……Page 220
Major Classes of Pathogenic Bacteria……Page 223
Antibiotic Treatment of Bacterial Infections……Page 231
Antibiotic Sensitivity Tests……Page 233
Adverse Effects of Antibiotics……Page 234
Chlamydiae……Page 235
Viruses……Page 236
Hemorrhagic Fevers……Page 237
Mode of Action……Page 239
Bodily Defenses Against Viral Infections……Page 241
Fungi……Page 242
Highly Pathogenic Fungi……Page 243
Treatment of Systemic Fungal Infections……Page 245
The Parasite and Its Host……Page 250
Malaria……Page 251
Amebiasis……Page 253
Leishmaniasis……Page 254
Giardiasis……Page 255
Cryptosporidiosis……Page 256
Roundworms……Page 257
Tapeworms……Page 260
Flukes……Page 261
Crab Louse Infestation……Page 262
Methods of Transmission……Page 266
Methods of Control……Page 268
Sexually Transmitted Diseases Other Than HIV……Page 270
Syphilis……Page 271
Gonorrhea……Page 273
Herpes……Page 275
Genital Chlamydial Infections……Page 277
HIV Transmission……Page 278
HIV Life Cycle……Page 279
Manifestations of HIV Infection……Page 280
Complications of AIDS……Page 282
Treatment of HIV Infection……Page 284
Cardiac Structure and Function……Page 290
Cardiac Valves……Page 291
Blood Supply to the Heart……Page 292
Conduction System of the Heart……Page 294
Blood Pressure……Page 295
The Electrocardiogram……Page 296
Echocardiography……Page 297
Cardiac Development and Prenatal Blood Flow……Page 298
Pathogenesis and Manifestations of Congenital Heart Disease……Page 300
Common Cardiovascular Abnormalities……Page 301
Cardiomyopathy……Page 306
Nonrheumatic Aortic Stenosis……Page 308
Mitral Valve Prolapse……Page 309
Prosthetic (Artificial) Heart Valves……Page 312
Infective Endocarditis……Page 313
Atrial Fibrillation……Page 315
Heart Block……Page 316
Myocardial Ischemia and Its Complications: A “Heart Attack”……Page 317
Cardiac Arrest……Page 318
Acute Coronary Syndrome……Page 319
Treatment of Acute Coronary Syndrome (Unstable Angina and Myocardial Infarcts)……Page 321
Location of Myocardial Infarcts……Page 323
Major Complications of Myocardial Infarcts……Page 324
Taking Aspirin to Reduce the Risk of Cardiovascular Disease……Page 325
Pathophysiology and Treatment……Page 326
Acute Pulmonary Edema……Page 327
Natriuretic Peptides in Heart Failure……Page 328
Blood Vessels……Page 334
Flow of Fluid Into and Out of Capillaries……Page 335
Circulatory Disturbances: Introduction……Page 336
Large Pulmonary Emboli……Page 337
Small Pulmonary Emboli……Page 338
Diagnosis of Pulmonary Embolism……Page 340
Treatment of Pulmonary Embolism……Page 341
Fat Embolism……Page 342
Varicose Veins……Page 343
Edema……Page 345
Pathogenesis and Classification of Edema……Page 346
Arterial Thrombosis……Page 348
Intracardiac Thrombosis……Page 349
The Response to Injury Hypothesis……Page 350
Natural History of Atherosclerosis……Page 352
Risk Factors for Atherosclerotic Disease: Introduction……Page 354
Blood Lipids……Page 355
Homocysteine……Page 357
Primary Hypertension……Page 358
Hypertension and the Aorta: Aneurysms……Page 359
Arteriosclerotic Aneurysm……Page 360
Dissecting Aneurysm of the Aorta……Page 361
Treatment of Coronary Artery Disease……Page 364
Composition and Function of Human Blood……Page 372
Normal Hematopoiesis……Page 375
Structure and Function of Hemoglobin……Page 376
Oxygen Transport by Hemoglobin……Page 377
Iron Metabolism and Hematopoiesis……Page 378
Methemoglobin……Page 379
Etiologic Classification of Anemia……Page 380
Iron Deficiency Anemia……Page 381
Vitamin B[sub(12)] and Folic Acid Deficiency……Page 383
Accelerated Blood Destruction……Page 385
Hereditary Hemolytic Anemias……Page 386
Acquired Hemolytic Anemia……Page 392
Secondary Polycythemia……Page 393
Thrombocytopenia……Page 394
The Lymphatic System……Page 395
Diseases of the Lymphatic System……Page 396
Classification of Leukemia……Page 397
Lymphomas……Page 402
Metastatic Tumors in Lymph Nodes……Page 403
Principles of Treatment……Page 404
Hematopoietc Stem Cell Therapy (Bone Marrow Transplantation)……Page 405
Description of Hemostasis……Page 412
Blood Vessels and Their Endothelial Lining……Page 413
Abnormalities of the Vessel Wall and Endothelial Cells……Page 414
Blood Vessels and Platelets……Page 415
Plasma Coagulation Factors……Page 416
Coagulation Inhibitors and Fibrinolysis……Page 417
Deficiency of Plasma Coagulation Factors……Page 418
Liberation of Procoagulant Material into The Circulation……Page 419
Laboratory Tests to Evaluate Hemostasis……Page 421
Structure and Function of the Lungs……Page 426
Bronchi, Bronchioles, and Alveoli……Page 427
Gas Exchange……Page 429
The Pleural Cavity……Page 430
Pulmonary Function Tests……Page 431
Pneumothorax……Page 432
Atelectasis……Page 434
Pneumonia……Page 435
Classification of Pneumonia……Page 436
Additional Lung Infections: SARS and MERS……Page 438
Tuberculosis……Page 439
Course of a Tuberculous Infection……Page 441
Drug-Resistant Tuberculosis……Page 443
Pulmonary Emphysema/Chronic Obstructive Lung Disease……Page 445
Derangements of Pulmonary Structure and Function in Emphysema……Page 446
Pathogenesis of Chronic Obstructive Pulmonary Disease……Page 447
Prevention and Treatment……Page 448
Respiratory Distress Syndrome of Newborn Infants……Page 449
Pulmonary Fibrosis……Page 451
Lung Carcinoma……Page 452
Structure and Physiology of the Breast……Page 460
Accessory Breasts and Nipples……Page 462
Fibroadenoma……Page 463
Carcinoma of the Breast……Page 464
Breast Carcinoma Susceptibility Genes……Page 465
Classification of Breast Carcinoma……Page 466
Evolution of Breast Carcinoma……Page 467
Mammograms……Page 468
Treatment……Page 470
Risks Related to Hormone Treatment……Page 474
The Menstrual Cycle……Page 480
Salpingitis and Pelvic Inflammatory Disease……Page 482
Condylomas of the Genital Tract and HPV Infection……Page 483
Vulvar Intraepithelial Neoplasia……Page 484
Cervical Intraepithelial Lesions (CIN)……Page 485
Diagnosis and Treatment of Cervical Dysplasia……Page 487
Benign Proliferative Changes in the Uterus……Page 488
Neoplastic Proliferative Changes in the Uterus……Page 489
Dysfunctional Uterine Bleeding……Page 491
Endometriosis……Page 492
Polycystic Ovary Syndrome……Page 494
Ovarian Neoplasms……Page 495
Contraception……Page 498
Emergency Contraception……Page 500
Development of Gametes and Fertilization……Page 506
Early Development of the Fertilized Ovum……Page 508
Duration of Pregnancy……Page 511
The Decidua……Page 514
The Chorion and Chorionic Villi……Page 515
The Placenta……Page 516
Polyhydramnios and Oligohydramnios……Page 518
Effects of Hyperglycemia on Pregnancy……Page 519
Spontaneous Abortion……Page 520
Ectopic Pregnancy……Page 521
Velamentous Insertion of the Umbilical Cord……Page 522
Placenta Previa……Page 523
Determination of Zygosity of Twins From Examination of Placenta……Page 524
Twin Transfusion Syndrome……Page 525
Conjoined Twins……Page 526
Toxemia of Pregnancy: Preeclampsia and Eclampsia……Page 527
Hydatidiform Mole……Page 528
Choriocarcinoma……Page 529
Hemolytic Disease of the Newborn (Erythroblastosis Fetalis)……Page 530
Prevention of RH Hemolytic Disease With RH Immune Globulin……Page 531
Treatment of Hemolytic Disease……Page 532
ABO Hemolytic Disease……Page 533
Role of the Kidneys……Page 538
Disturbances of Water/Electrolyte Balance……Page 539
Renal Regulation of Blood Pressure, Blood Volume, and Blood pH……Page 540
Regulation of Blood pH……Page 541
The Kidneys……Page 543
The Nephron……Page 544
Developmental Disturbances……Page 548
Nephropathies: An Introduction……Page 549
Glomerulonephritis……Page 550
Nephrotic Syndrome……Page 554
Arteriolar Nephrosclerosis……Page 555
Diabetic Nephropathy……Page 556
Acute Renal Tubular Injury……Page 557
Cystitis……Page 558
Pyelonephritis……Page 559
Urolithiasis……Page 560
Obstruction……Page 562
Congenital Polycystic Kidney Disease……Page 563
Renal Cortical Tumors……Page 564
Chronic Renal Failure……Page 565
Hemodialysis……Page 567
Renal Transplantation……Page 569
Urinalysis……Page 570
Additional Techniques……Page 571
Structure and Function of the Male Reproductive Organs……Page 578
Gonorrhea and Nongonococcal Urethritis……Page 581
Nodular Hyperplasia of the Prostate (Benign Prostatic Hyperplasia)……Page 582
Adenocarcinoma of the Prostate……Page 583
Carcinoma of the Testis……Page 586
Congenital Disorders of Penile Development……Page 587
Cryptorchidism……Page 588
Hydrocele……Page 589
Physiology of Penile Erection……Page 590
Treatment……Page 592
Structure and Function of the Liver……Page 596
Causes and Effects of Liver Injury……Page 597
Viral Hepatitis……Page 600
Clinical Manifestations and Course……Page 601
Hepatitis B……Page 602
Hepatitis C……Page 605
Hepatitis E……Page 606
Fatty Liver……Page 607
Alcoholic Liver Disease……Page 608
Nonalcoholic Liver Disease……Page 609
Impaired Liver Function……Page 610
Portal Hypertension……Page 612
Hepatic Encephalopathy……Page 614
Procedures to Treat Manifestations of Cirrhosis……Page 615
Formation and Excretion……Page 616
Biliary Cirrhosis……Page 617
Secondary (Obstructive) Biliary Cirrhosis……Page 618
Factors Affecting The Solubility of Cholesterol in Bile……Page 619
Formation of Gallstones……Page 620
Complications of Gallstones……Page 621
Tumors of the Liver……Page 622
Structure and Function of the Pancreas……Page 628
Acute Pancreatitis……Page 629
Cystic Fibrosis of the Pancreas……Page 630
Role of Insulin in Metabolism……Page 632
Diabetes Mellitus……Page 633
Type 1 Diabetes Mellitus……Page 634
Type 2 Diabetes Mellitus……Page 635
Gestational Diabetes……Page 637
Monitoring Control of Diabetes……Page 638
Complications of Diabetes……Page 639
Hypoglycemia……Page 640
Tumors of the Pancreas……Page 641
Cleft Lip and Cleft Palate……Page 646
Abnormalities of Tooth Development……Page 648
Tumors of the Oral Cavity……Page 650
Cardiac Sphincter Dysfunction……Page 651
Gastric Mucosal Tears……Page 653
Gastritis……Page 654
Peptic Ulcer……Page 656
Acute Viral Gastroenteritis……Page 657
Disturbances of Bowel Function: Food Intolerance……Page 659
Gluten Intolerance……Page 660
Irritable Bowel Syndrome……Page 661
Chronic Enteritis……Page 662
Treatment of Chronic Enteritis……Page 664
Intestinal Obstruction……Page 665
Mesenteric Thrombosis……Page 669
Diverticulosis and Diverticulitis……Page 670
Tumors of the Bowel……Page 671
Imperforate Anus……Page 673
Hemorrhoids……Page 674
Obesity……Page 676
Anorexia Nervosa and Bulimia Nervosa……Page 679
Causes of Malnutrition……Page 680
Endocrine Functions and Dysfunctions……Page 686
The Pituitary Gland……Page 688
Physiologic Control of Pituitary Hormone Secretion……Page 691
Pituitary Hypofunction……Page 692
Pituitary Tumors……Page 693
Overproduction of Prolactin……Page 694
The Thyroid Gland……Page 696
Goiter……Page 697
Hyperthyroidism……Page 699
Hypothyroidism……Page 701
Chronic Thyroiditis: Hashimoto Thyroiditis……Page 702
Tumors of the Thyroid……Page 703
Hyperparathyroidism……Page 705
The Adrenal Cortex……Page 706
Disturbances of Adrenal Cortical Function……Page 707
The Adrenal Medulla……Page 711
The Gonads……Page 712
Stress and the Endocrine System……Page 713
Structure and Function……Page 720
Interaction of Nervous System with Muscles……Page 723
Development of the Nervous System……Page 724
Neural Tube Defects……Page 725
Spina Bifida……Page 726
Prenatal Detection of Neural Tube Defects……Page 727
Hydrocephalus……Page 728
Cerebral Injury……Page 730
Stroke……Page 732
Cerebral Thrombi……Page 733
Stroke Caused by Arteriosclerosis of Extracranial Arteries……Page 734
Cerebral Hemorrhage……Page 735
Manifestations of Stroke……Page 736
Transient Ischemic Attack……Page 737
Cerebral Aneurysm……Page 738
Infections of the Nervous System……Page 740
Meningitis Caused by Bacteria and Fungi……Page 741
Viral Infections……Page 742
Poliomyelitis……Page 743
Manifestations of Prion Infection……Page 744
Creutzfeldt-Jakob Disease……Page 745
Mad Cow Disease……Page 746
Alzheimer Disease……Page 747
Multiple Sclerosis……Page 748
Parkinson Disease……Page 750
Huntington Disease……Page 751
Motor Neuron Degenerative Disease (ALS)……Page 752
Peripheral Nerve Tumors……Page 753
Tumors of the Brain……Page 754
Polyneuropathies (Peripheral Neuritis)……Page 755
Peripheral Nerve Injury……Page 756
Structure and Function of the Skeletal System……Page 762
Bone Growth and Remodeling……Page 766
Bone Growth Disturbances Caused by Vitamin D Deficiency: Rickets and Osteomalacia……Page 767
Abnormal Bone Formation……Page 768
Congenital Clubfoot (Talipes)……Page 770
Congenital Dislocation of the Hip……Page 771
Rheumatoid Arthritis……Page 772
Osteoarthritis……Page 775
Gout……Page 777
Fracture of Bone……Page 780
Hematogenous Osteomyelitis……Page 781
Clinical Manifestations and Treatment……Page 782
Tumors of Bone……Page 783
Metabolic Bone Disease: Osteoporosis……Page 785
Structure and Function of the Spine……Page 786
Scoliosis……Page 788
Intervertebral Disk Disease……Page 790
Chest Wall Abnormalities……Page 791
Connective Tissue Disease……Page 793
Factors Affecting Muscular Structure and Function……Page 794
Generalized Myositis……Page 796
Muscular Dystrophy……Page 797
Myasthenia Gravis……Page 798
A……Page 804
B……Page 806
C……Page 807
D……Page 809
E……Page 810
G……Page 812
H……Page 814
I……Page 815
L……Page 816
M……Page 817
O……Page 819
P……Page 820
R……Page 822
S……Page 823
T……Page 825
V……Page 826
Z……Page 827
A……Page 828
B……Page 830
C……Page 831
D……Page 833
E……Page 834
F……Page 835
G……Page 836
H……Page 837
I……Page 839
L……Page 840
M……Page 841
N……Page 842
P……Page 843
R……Page 845
S……Page 846
T……Page 847
V……Page 848
Z……Page 849

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